I have applied for hundreds of jobs but have not heard back. What am I doing wrong?

For job applications, focus on quality not quantity. Tailor every résumé and cover letter in your application process. Study the job description and make sure you are applying for jobs where you match the experience the company is seeking. Use the job description to highlight specific skills listed. Lastly, either start networking or ramp up your networking as it is often the key to getting past the application to the interview invitation.